Why Mayo Clinic
- Medical: Multiple plan options.
- Dental: Delta Dental or reimbursement account for flexible coverage.
- Vision: Affordable plan with national network.
- Pre-Tax Savings: HSA and FSAs for eligible expenses.
- Retirement: Competitive retirement package to secure your future.
Responsibilities
Position Summary
The Senior Principal AI/ML Engineer for AI Representation & EMR Vectorization is the senior technical leader and lead scientist responsible for architecting Mayo Clinic’s unified multimodal EMR representation layer. This role defines and builds the scientific substrate used by foundational models, clinical agents, and research applications. The individual serves as a hands-on expert and player-coach, guiding technical strategy while contributing directly to model development, graph construction, and representation science. Over time, this position will build and lead a specialized team.
Key Responsibilities
Scientific & Technical Leadership
- Design and implement Mayo’s multimodal EMR representation AI architecture, including text, imaging, waveform, structured data, temporal sequences, and multi-visit trajectories.
- Develop graph-based representations and knowledge graphs linking patients, events, attributes, clinical concepts, and embeddings.
- Integrate graph reasoning, vector similarity search, and hybrid vector–graph pipelines for retrieval-augmented models and agentic reasoning.
- Define standards for temporal modeling, drift-aware embeddings, and sequence alignment across encounters.
Hands-On Modeling & Engineering
- Build large-scale embedding pipelines using transformer-based models, contrastive learning, graph neural networks, and hybrid architectures.
- Implement efficient query layers using vector stores and graph databases.
- Develop interpretable embedding diagnostics, attribution tools, and graph-based audits to enable safe clinical use.
- Explore and implement methods for explaining similarity, graph traversals, temporal evolution, and patient-neighborhood reasoning.
Cross-functional Collaboration
- Work with AI researchers on specialty-specific embeddings, representation refinement, and research prototypes.
- Collaborate with clinicians to operationalize clinically meaningful features, phenotypes, and longitudinal concepts.
- Provide scientific input to the Foundational Model Science Program to ensure alignment between representations and model architectures.
Team Leadership
- Serve as founding technical lead of the Reasoning EMR Representation team.
- Mentor junior scientists and engineers; build a future team specializing in representation learning and graph-based reasoning.
Qualifications
Required
Preferred
- PhD or Master’s in Computer Science, Machine Learning, Biomedical Engineering, or related field.
- 10+ years experience building production ML systems, including multimodal architectures and representation learning.
- Experience with EMR data, healthcare multimodality, or clinical data integration.
- Experience building patient similarity models, temporal embedding systems, or phenotype discovery pipelines.
- Strong background in explainability, causality, or interpretable ML.
- Prior experience in a player–coach or team-lead role.
Exemption Status
Exempt
Compensation Detail
Education, experience and tenure may be considered along with internal equity when job offers are extended.; $175,406-263,099 annually
Benefits Eligible
Yes
Schedule
Full Time
Hours/Pay Period
80
Schedule Details
Monday – Friday regular day hours
Weekend Schedule
none expected
International Assignment
No
Site Description
Equal Opportunity
Recruiter
Jill Squier
Source link
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