Why Mayo Clinic
- Medical: Multiple plan options.
- Dental: Delta Dental or reimbursement account for flexible coverage.
- Vision: Affordable plan with national network.
- Pre-Tax Savings: HSA and FSAs for eligible expenses.
- Retirement: Competitive retirement package to secure your future.
Responsibilities
We are seeking a highly motivated and detail-oriented Research Technologist to join our translational neuro-oncology research team. Our lab focuses on glioblastoma and peripheral nerve sheath tumors, with a strong emphasis on tumor microenvironment biology, spatial and single-cell transcriptomics, hypoxia signaling, and molecular biomarker discovery.
The successful candidate will support ongoing projects by performing established and emerging laboratory techniques, including but not limited to:
- Molecular biology assays (PCR, Western blotting, RNA/DNA extraction, qPCR)
- Immunohistochemistry and immunofluorescence staining on FFPE and frozen tissues
- Human and murine cell culture (including primary tumor-derived lines)
- Fluorescence and brightfield microscopy, image acquisition, and analysis
- Mouse handling and tissue processing (training provided if needed)
- Sample preparation for spatial transcriptomics, single-cell analysis, and next-generation sequencing
- Data entry, preliminary statistical analysis, and assistance with manuscript and figure preparation
- Organization of lab inventory, reagents, and general lab maintenance
The Research Technologist will present data in lab meetings, assist with experimental planning, and collaborate closely with senior lab members and trainees. The candidate will be expected to work independently on routine procedures and receive mentorship for more complex tasks. Opportunities for authorship on publications are available based on contributions.
Qualifications
Basic Qualifications:
Requires bachelor’s degree in biology, chemistry, other relevant science, or an associates degree with 6 years of relevant laboratory experience. Must exhibit a solid understanding of lab techniques, equipment, and safety. Must have the ability to organize and carry out laboratory techniques independently and in a team setting. Experience with basic data analysis is required. This position requires demonstrated writing skills.
Preferred Qualifications:
- Bachelor’s degree in biology, biomedical sciences, or a related field is required (Master’s degree or relevant research experience preferred)
- Minimum of 3 year of hands-on wet lab experience (academic or industry); associate degree with extensive relevant lab experience will also be considered
- Proficiency in standard molecular biology techniques and mammalian cell culture
- Familiarity with immunostaining, microscopy, and basic data analysis (GraphPad, ImageJ, Excel/R)
- Excellent organizational skills, attention to detail, and ability to work both independently and collaboratively
- Strong communication and documentation skills
Experience with tissue sectioning, digital pathology, or prior exposure to spatial transcriptomics or single-cell workflows is an asset but not required. Training will be provided.
Exemption Status
Nonexempt
Compensation Detail
Education, experience and tenure may be considered along with internal equity when job offers are extended.; $27.44-41.16/ hour
Benefits Eligible
Yes
Schedule
Full Time
Hours/Pay Period
80
Schedule Details
M-F day hours
Weekend Schedule
Occasional as necessary for the research.
International Assignment
No
Site Description
Equal Opportunity
Recruiter
Jill Squier
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